By
By
Sampson Onwuka
Vaccination…
OUF.)
In keeping to themes of 2014
August 12th, and the injunctions justifying great periods in the annals of
world history, we can begin from May 15, 2015, to attempt a public analyses of
the theories involving HIV and how it can finally be set aside for all times.
Drawn from the piece from last year, we can recall that the emphasis on Polio
Virus was the author’s systematic strategy in analyzing some of the gaps and
deficiencies that bar the final solutions for Interleukin-2 virus and HIV. The author
classified HIV as a blood cancer was no new article of faith, it was driven
perhaps by lateral arguments on Lentivirus and the slow Visna virus some of the
slow virus is perhaps due to the origins of the strains. One of the flim-flam
from Robert Gallo is the attempt at correlating Cancer or Oncogenic viruses and
HIV, that is the rate at which Oncogenic and Lentiviruses such Visna are
considered slow virus and may have a few things to do with HIV AIDS. Put it
differently, it is important that we must necessarily understand that the
process and complication of thymus as a sugar complex and its relations to CD4 –
understand the penetration of the human immune system by locally manufactured
foreign virus (HIV) and the gradual evolution of a prophage whose life retains
a DNA from previous reproductive process gives us the impression of Immune
Deficiency that is determined by the ability of existing DNA and genetic
substance – Cytosine, Guanine, Adenine and Thymine. A recent account on this
episode is through; Genetics Home Reference that “DNA bases pair up with each
other, A with T and C with G, to form units called base pairs. Each base is
also attached to a sugar molecule and a phosphate molecule. Together, a base,
sugar, and phosphate are called a nucleotide.” The book explains the particular
kind of sugar dissolving bacteria that can be considered – part and central to
these processes – especially the introduction of Avery Oswald, Alfred and
Martha Chase well received experiment and the result of an experiment by French
scientist Andrew Lwdolf, Jacque Monod and Maurice Francoise, especially Jacque
Monod, who placed several emphasis on E.coli and its adaptive enzyme to sugar.
Not enough have changed since then but the
complex put to together, a base, sugar, and phosphate define nucleotide, illustrate
the role of Thymus in rebuilding human DNA, that the complex breakdown and
regeneration of life is a well-considered responsibility among the primary
chemicals in the body and in the case of Bromide-5-Methylation, the process of
adapting the body to new realities of foreign antigen – usually part of the
digestive system is achieved by Thymus or CD4s, which link the DNA of foreign
intruder to human DNA thereby hosting immune response. Naturally the body has
no mean defensive device saving for its reaction to intrusion – mainly due to
the structure of human DNA that is perpetually in such motion that new antigen
tend to interfere, tend to delay information through RNA, and in the end, alter
the dynamics of the body. We are naturally sick from any hint of interference to
human system – environment plays a part and the body releases enzyme or
proteins to auto repair by acting as bi-product for the gaps in RNA
communication. An elementary knowledge of the role of proteins, vitamins and
nutrients is that they help to replenish the body by introducing extra help
which weaken DNA bonds such as thymus can canter to.
In one recent book by Leanne K.
Currie-McGhee (2008) that “HIV replicates itself by inserting its RNA into a
cell’s DNA. When the cell divides, a new copy of the Virus is produced. This
increases the amount of HIV in a person. HIV then attacks CD4 cells, also known
as T Cells. T Cells are immune cells that fight off illnesses. When HIV hijacks
these cells, the body loses its ability to fight off illnesses. AZT blocks the
replication of HIV. As a result, AZT decreases the amount of HIV in the body
and increases a person’s healthy CD4 cell count.” While this is a good summary
of the operational dynamics of HIV, it hardly tells any stories about human health,
and does not do much good to any scientist interest in exploring new ideas.
From her book we learn the current classes of HIV medications; Non-nucleoside
reverse transcriptase (NNRTIs), (2) Non-nucleoside reverse transcriptase
inhibitors (NRTIs), (3) Protease Inhibitors and (4) Fusion Inhibitors, all of
which work to perform one function; stop HIV multiplication. She then adds the
struggling function of the various groups of medication that “NNRTIs and NRTIs
are both reverse transcriptase inhibitors that stop viral RNA from being turned
into DNA. The nucleoside and non-nucleoside reverse transcriptase inhibitors
target slightly different parts of the enzyme. Protease inhibitors prevent the
HIV Virus from forming mature Virions. Fusion inhibitors stop HIV from actually
entering CD4 cells.” Such summary of the whole process is acceptable in understanding
the current medication with Virus, but does not nearly open the discussion to
further treatment, it does not nearly deal with the issues arising from
knowledge on H.I.V. In reality, there is more to be desired about the patient
to patient experience which HIV communities can offer, for instance the impact
of new but also old drugs on these patient, and why these drugs offer a future
that encourages replications if not control at the virions level, why there are
problems of handling the virus. Put it bluntly, the emphasis on cocktails and its
combinations are attempt at final cases of the HIV patient, whereas the main
attention is not only the mode of transmission or the pathology of virus,
rather, why HIV virus only affect human beings.
There are so much that enter
public discussion on HIV, but half of the standard procedure for handling the
virus – beginning with prescription for HIV Patient cover two major categories,
the Nuke and None Nuke and in the words of Magic Johnson, there are more than
22 specialist products on HIV, including AZT – (Zidovudine or Azidothymidine)
approved in 1987 by FDA, used on farm animals, primarily popular in the 90’s,
popular in New York and renown for poisonous, and remained for a long time the
major problem with Food and drug administration. But from the sciences involved
in understanding HIV and the treatment that followed, these products types are
probably similar in essence and cover at least three major aspects of the HIV
treatment, from inhibiting the growth of the Virus to the aiding the CD4s in
its attempt in reducing the efficacy of the Viral load at any level of its
existence. The last basic determinative of the designer drug is suffocating the
maturity of the virions into adult virus – delaying its destructive adult
stages. Whatever may be the nature of the Virus and the attention of drug
companies, the attempt at inhibiting the progress of the Virus and the use of
AZT in normalizing the function of the body or hormones in the body and its CD4
responses will only delayed the end.
It is the expectation of medical
profession that if the Baby Virions are kept at the lows level of maturity, it
may prove less destructive to the system or the body, proving in certain cases
that the drug may lengthen the life of a victim. The earliest patients were known not to have died from the virus
itself suggesting to scientist that perhaps that preventing the HIV from
profligate activity was more rewarding than the cure. What exactly killed HIV
patient – assuming the HIV was not lethal and the virus slow in its
destruction? The patient dies from other infections other than self was one of
the central puzzles that defied the earliest years of the pandemic. The challenge is how to overcome the pandemic
and to end the most demanding infection other than cancer. There are great many
stories regarding the behavior of AIDS patient. Some of the dread over HIV was
due to its presence in “FECES – Nasal fluid”, in the Saliva of the patient,
including – ‘sweat, tears, urine’, some of the cases of the dread involve use
of “Urine – Vomit, “Vomit – slight chance with blood on it”, and other body
fluids (1) Amniotic fluids, (2) “cerebrospinal fluid” and (3) synovial fluid”.
To manage the cycle of
information which does not die easy – especially with the pandemic that took
American by storm, some of the early claims about earlier (viruses) or
infections need to be drawn, part of which is how and to what extent the virus
defies the system. Perhaps in this account, some of the general definition on
the virus leads us to emphasize the commitment of its earliest scientist to
finding a cure. There is nothing displaced about champions such as Watson and
Crick, for instance, these men were alive at the time of the pandemic and
struggled to provide the answer but how the virus took a shine off their
brilliance has not been well discussed, above all, how some of their drives
with HIV provided paved the way for other experiments. The shift in the focus
of the study of HIV is perhaps due to other civil strife. It is worth the time
to return to the early years of the pandemic and pull straws on what the
Scientist did, when and how. Accounts of the DNA discoveries (A) James Watson
(b) Francis Crick is still popular – so also the story of the Alpha Helix, the
accounts on Haemoglobin and the accounts of Linus Pauling including his work on
Sickle Cells, HPA 22 Insulin (Diabetes), Insulin – including the work of
Jacques Monod and his E. Coli Phage Diabetes – some of which is reach back to Oswald
Avery (S-strain, Streptococcus, E Coli Phage Virus,..) part of which is the
story of Vaccination leading in case to John
Enders, James Salk, Albert Sabin, Tuberculosis…
.The standard techniques for
studying new pandemics is not unknown, but the relevant questions are still
useful, that is, what happens or happened during periods of epidemics such as
flu-virus? How does that relate to pandemic such as EBV or in our studies, HIV?
How does the story of Polio and period of cold virus prove a point of interest
for those who ventured into Africa in search of the origins of HIV? Since the
scientist driven from their home land, and write back to the States, where
these scientist interested in major themes on HIV or he experiment with
vaccination proved a point for evolution and studies in anthropology. HIV is argued
to have origins in other creatures and remains for many of us a point of dissent.
The theory has political stay, and there are few believers in that such
theories on Zaire strain, may be correct, fewer will accept that perhaps the
African dissent on the origins of HIV is perhaps misleading - if not untrue. The
role of enzyme in the blood is important – the role of oxygen in the blood is
also important, but the link to thymus and link with E Coli phage bacteria or
sugar mulching prophage may yet gain acceptance. The profligate behavior of
E.coli naturally involves the reduction of sugar – they feed on sugar molecules
thereby preventing the normal molecule structure of the Carbon ( ) DNA especially thymus.
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